April 20, 2007, Newsletter Issue #36: Targeting Genes as Sources for Autism
Tip of the Week
There are specific genes found on five different chromosomes that are thought by some researchers to have a direct link to autism. The chromosomal regions are: chromosome 2, 3, 7 and 15 as well as the X chromosome. Let's break down the different regions:
Chromosome 2 and 7 seem to be linked in some studies of autistic disorder according to a 2001 article from the Nation Institutes of Health, . Chromosome 7 is associated with language development and it seems to be a factor in some studies but not in others. Chromosome 2 is the second larges chromosome in the human genome. Researches are interested in the interrelation of genes on these two chromosomal regions as a possible cause for autistic disorder.Chromosome 3 contains genes that are associated with early brain development as well as brain messaging. Dysfunction in these genes may cause mixed messages in the brain cells and improper early brain development.Duplications of chromosome 15 may be associated with a lack of language skills, seizures and anxiety according to an article by Hugh McIntosh.
The X chromosome is directly linked to Rett's disorder. This developmental disorder fall within that autism spectrum. Rett's syndrome is more common in females because the condition is fatal in males. Chromosome X is also linked to the chemical messages passed in the central nervous system. Genes located on this chromosome make proteins called neuroligins. These proteins work with the centarl nervous system to help cells chemically communicate with each other.
Some of the suspect genes are classified as positional candidate genes while others are considered functional candidate genes.
About LifeTips
Now one of the top on-line publishers in the world, LifeTips offers tips to millions of monthly visitors. Our mission mission is to make your life smarter, better, faster and wiser. Expert writers earn dough for what they know. And exclusive sponsors in each niche topic help us make-it-all happen.
